Сергей Александрович Окороченков

кандидат химических наук    /    Russian Federation, Moskau


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Synthesis and antifungal properties of arginine-containing hemin derivatives

G. A. Zheltukhina • S. A. Okorochenkov • N. V. Groza • V. G. Arzumanyan • V. E. Nebolsin
Due to a steadily increasing number of clinical isolates of microscopic fungi that show resistance to conventionally administered antimycotics, the specialists involved have constantly been searching for novel fungicidal agents among various classes of chemical compounds. The present study was...

Relationship between SelfOrganization, Physicochemical Properties, and Biological Activity of Aqueous Solutions of Hemin Derivatives

I. S. Ryzhkina, Yu. V. Kiseleva, G. A. Zheltukhina, S. A. Okorochenkov, L. I. Murtazina, A. P. Timosheva, V. E. Nebolsin, and Academician A. I. Konovalov
The aim of this work was to reveal specific features of self-organization of highly diluted aqueous solutions of two hemin derivatives in a concentration range of 10^–17–10^–3 mol/L, study concentration dependences of physicochemical properties of hemin derivative solutions (electric...
Doklady Physical Chemistry, 2011, Vol. 440, Part 1, pp. 157–161.

Antimicrobial Peptides: the Mode of Action and Perspectives of Practical Application

S. A. Okorochenkov , G. A. Zheltukhina, and V. E. Nebol’sin
This review deals with antimicrobial peptides (AMPs) that demonstrate antibacterial, antiviral, and antifungal activity. It considers structure and mechanism of AMP interaction with lipid membrane and intracellular targets of pathogens. Special attention is paid to modern state and perspectives...
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2011, Vol. 5, No. 2, pp. 95–102.
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